Oncology

Date

14/15 September 2020

Place

Lausanne (exact location will be announced soon)

Language

English

Goals of the module

Participants

  • have an overview on sex differences in oncology and the scientific, clinical and societal implications of sex differences for prevenetion, diagnosis and treatment of cancer.
  • are familiar with the combined impact of sexual hormones and sex chromosomes on cancer susceptibility with a focus on intrinsic control of cancer initiating cell populations, tumor microenvironment and systemic determinants of cancer development.

Content of the module

  • Rationale for considering gender in cancer prevention and treatment
        • Sex differences in epidemiology of various cancers
        • Sex and gender differences in carcinogen exposition (UV light, smoking, environmental carcinogens)
  • Sex chromosomes and their impact on cancer susceptibility
      • Estrogens and their impact on cancer risk in females and males
      • Endocrine disruptors
      • Androgens and their impact on cancer risk in females and males
  • Impact of sex on systemic determinants of cancer development
    • immunity
    • tumor microenvironment
    • cancer initiating cells
    • metabolism
    • microbiome
  • Clinical implications of sex and gender differences in cancer
    • Sex differences in response and toxicity of anticancer therapies (cytotoxics, targeted therapies and immunotherapies)
    • Sex differences in oncological surgery and radiotherapy outcomes
    • Implications for clinical trial design and reporting of results
    • Sex-specific drug dosing strategies?
    • Sex-specific cancer prevention efforts?

 Lecturers

Prof. Dr. Paolo Dotto, Department of Biochemistry, University of Lausanne/ International Cancer Prevention Institute (Chair)

Dr. med. Berna Özdemir, Department of Oncology, Lausanne University Hospital and University of Lausanne/ International Cancer Prevention Institute

PD Dr. med. Anna Wagner, Department of Oncology, Lausanne University Hospital and University of Lausanne

Registration form

Registration form

Deadline

14 August 2020